Histone H2A.Z Recombinant Rabbit mAb
Cat No.: ARM2687
Size：
| Product Name: | Histone H2A.Z Recombinant Rabbit mAb |
| Cat No.: | ARM2687 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB, IHC, ICC/IF |
| clonality: | Monoclonal |
| recommended dilution: | WB, IHC, ICC/IF |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Histone H2A.Z |
| calculated molecular weight: | 14 kDa |
| observed molecular weight: | 14 kDa |
| genbank accession number: | P0C0S5 |
| gene id (ncbi): | 3015 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | H2AZ; H2A.z; H2A/z; H2A.Z-1 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008] |