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SET Recombinant Rabbit mAb

Cat No.: ARM2685
Size:
Product Name: SET Recombinant Rabbit mAb
Cat No.: ARM2685
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB, IHC, ICC/IF, FC, IP
clonality: Monoclonal
recommended dilution: WB, IHC, ICC/IF, FC, IP
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human SET
calculated molecular weight: 34 kDa
observed molecular weight: 39 kDa
genbank accession number: Q01105
gene id (ncbi): 6418
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: 2PP2A; IGAAD; TAF-I; I2PP2A; IPP2A2; PHAPII; TAF-IBETA
category: Primary Ab
concentration: 1mg/ml
background: The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]