C4 binding protein Recombinant Rabbit mAb
Cat No.: ARM2492
Size:
Product Name: | C4 binding protein Recombinant Rabbit mAb |
Cat No.: | ARM2492 |
source: | Rabbit |
reactivity: | Human, Rat |
applications: | WB,IHC,ICC/IF,IP |
clonality: | Monoclonal |
recommended dilution: | WB,IHC,ICC/IF,IP |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of human C4 binding protein |
calculated molecular weight: | 28 kDa |
observed molecular weight: | 40 kDa |
genbank accession number: | P20851 |
gene id (ncbi): | 725 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | C4BP |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq, Jul 2008] |