C4 binding protein Recombinant Rabbit mAb
Cat No.: ARM2492
Size：
| Product Name: | C4 binding protein Recombinant Rabbit mAb |
| Cat No.: | ARM2492 |
| source: | Rabbit |
| reactivity: | Human, Rat |
| applications: | WB,IHC,ICC/IF,IP |
| clonality: | Monoclonal |
| recommended dilution: | WB,IHC,ICC/IF,IP |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human C4 binding protein |
| calculated molecular weight: | 28 kDa |
| observed molecular weight: | 40 kDa |
| genbank accession number: | P20851 |
| gene id (ncbi): | 725 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | C4BP |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq, Jul 2008] |