RGS6 Recombinant Rabbit mAb
Cat No.: ARM2453
Size:
Product Name: | RGS6 Recombinant Rabbit mAb |
Cat No.: | ARM2453 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB |
clonality: | Monoclonal |
recommended dilution: | WB |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human RGS6 |
calculated molecular weight: | 54 kDa |
observed molecular weight: | 54 kDa |
genbank accession number: | P49758 |
gene id (ncbi): | 9628 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | GAP; S914; HA117 |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.[provided by RefSeq, Mar 2011] |