Ku70 Recombinant Rabbit mAb
Cat No.: ARM2331
Size:
Product Name: | Ku70 Recombinant Rabbit mAb |
Cat No.: | ARM2331 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IHC,ICC/IF |
clonality: | Monoclonal |
recommended dilution: | WB,IHC,ICC/IF |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Ku70 |
calculated molecular weight: | 70 kDa |
observed molecular weight: | 70 kDa |
genbank accession number: | P12956 |
gene id (ncbi): | 2547 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | ML8; KU70; TLAA; CTC75; CTCBF; G22P1 |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008] |