Tissue Factor Pathway Inhibitor Recombinant Rabbit mAb
Cat No.: ARM2271
Size：
| Product Name: | Tissue Factor Pathway Inhibitor Recombinant Rabbit mAb |
| Cat No.: | ARM2271 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB |
| clonality: | Monoclonal |
| recommended dilution: | WB |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human TFPI |
| calculated molecular weight: | 35 kDa |
| observed molecular weight: | 40-55 kDa |
| genbank accession number: | P10646 |
| gene id (ncbi): | 7035 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | EPI; TFI; LACI; TFPI1 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016] |