IMPDH2 Recombinant Rabbit mAb
Cat No.: ARM2256
Size:
Product Name: | IMPDH2 Recombinant Rabbit mAb |
Cat No.: | ARM2256 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,ICC/IF,FC,IP |
clonality: | Monoclonal |
recommended dilution: | WB,IHC,ICC/IF,FC,IP |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human IMPDH2 |
calculated molecular weight: | 56 kDa |
observed molecular weight: | 56 kDa |
genbank accession number: | P12268 |
gene id (ncbi): | 3615 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | IMPD2; IMPDH-II |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5---monophosphate into xanthine-5---monophosphate, which is then converted into guanosine-5---monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008] |