AP3M1 Recombinant Rabbit mAb
Cat No.: ARM2087
Size:
Product Name: | AP3M1 Recombinant Rabbit mAb |
Cat No.: | ARM2087 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,ICC/IF,FC |
clonality: | Monoclonal |
recommended dilution: | WB,ICC/IF,FC |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human AP3M1 |
calculated molecular weight: | 47 kDa |
observed molecular weight: | 47 kDa |
genbank accession number: | Q9Y2T2 |
gene id (ncbi): | 26985 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | AP-3 adaptor complex mu3A subunit; Mu-adaptin 3A; Mu3A-adaptin |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane, and it may directly function in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2016] |