PCGF6 Recombinant Rabbit mAb
Cat No.: ARM1997
Size:
Product Name: | PCGF6 Recombinant Rabbit mAb |
Cat No.: | ARM1997 |
source: | Rabbit |
reactivity: | Mouse, Rat |
applications: | WB,ICC/IF,IP |
clonality: | Monoclonal |
recommended dilution: | WB,ICC/IF,IP |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of mouse PCGF6 |
calculated molecular weight: | 40 kDa |
observed molecular weight: | 40 kDa |
genbank accession number: | Q99NA9 |
gene id (ncbi): | 71041 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | MBLR; Rnf134; AI604840; 4933407A11Rik |
category: | Primary Ab |
concentration: | 1mg/ml |
background: | Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A --Lys-119--, rendering chromatin heritably changed in its expressibility. Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity. |