NR2C2 Rabbit pAb
Cat No.: APA4543

Product Name: | NR2C2 Rabbit pAb |
Cat No.: | APA4543 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:2000 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human NR2C2 |
calculated molecular weight: | 65 kDa |
observed molecular weight: | 65 kDa |
genbank accession number: | P49116 |
gene id (ncbi): | 7182 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | TR4; TAK1 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014] |