CD89 Rabbit pAb
Cat No.: APA4530

Product Name: | CD89 Rabbit pAb |
Cat No.: | APA4530 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IHC,ICC/IF,FC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000-1:5000 IHC: 1:50-1:200 ICC/IF: 1:50-1:200 FC: 1:20 IP: 1:20-1:50 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human CD89 |
calculated molecular weight: | 32 kDa |
observed molecular weight: | 55-70 kDa |
genbank accession number: | P24071 |
gene id (ncbi): | 2204 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | CD89; FcalphaRI; CTB-61M7.2 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |