TRADD Rabbit pAb
Cat No.: APA4505

Product Name: | TRADD Rabbit pAb |
Cat No.: | APA4505 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,ICC/IF,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:20 ICC/IF: 1:20 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human TRADD |
calculated molecular weight: | 34 kDa |
observed molecular weight: | 34 kDa |
genbank accession number: | Q15628 |
gene id (ncbi): | 8717 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | Hs.89862 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008] |