Ionotropic Glutamate receptor 4 Rabbit pAb
Cat No.: APA4413

Product Name: | Ionotropic Glutamate receptor 4 Rabbit pAb |
Cat No.: | APA4413 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000-1:5000 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Ionotropic Glutamate receptor 4 |
calculated molecular weight: | 101 kDa |
observed molecular weight: | 101 kDa |
genbank accession number: | P48058 |
gene id (ncbi): | 2893 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | GLUR4; GLURD; GluA4; GLUR4C |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq, Jul 2008] |