IL18 binding protein Rabbit pAb
Cat No.: APA4396

Product Name: | IL18 binding protein Rabbit pAb |
Cat No.: | APA4396 |
source: | Rabbit |
reactivity: | Human, Rat |
applications: | WB,IHC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000-1:2000 IHC: 1:50 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human IL18 binding protein |
calculated molecular weight: | 21 kDa |
observed molecular weight: | 44 kDa |
genbank accession number: | O95998 |
gene id (ncbi): | 10068 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | IL18BPa |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn--s disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011] |