Integrin alpha 6 Rabbit pAb
Cat No.: APA4199
Size：
| Product Name: | Integrin alpha 6 Rabbit pAb |
| Cat No.: | APA4199 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:20-1:500 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Integrin alpha 6 |
| calculated molecular weight: | 127 kDa |
| observed molecular weight: | 127 kDa |
| genbank accession number: | P23229 |
| gene id (ncbi): | 3655 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | CD49f; VLA-6; ITGA6B |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] |