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IL18 Rabbit pAb

Cat No.: APA3875
Size:
Product Name: IL18 Rabbit pAb
Cat No.: APA3875
source: Rabbit
reactivity: Mouse
applications: WB,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
IP: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of mouse IL18
calculated molecular weight: 22 kDa
observed molecular weight: 22 kDa
genbank accession number: P70380
gene id (ncbi): 16173
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: Igif; Il-18
category: Primary Ab
concentration: 0.5mg/ml
background: A proinflammatory cytokine primarily involved in polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells.
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