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Dystrophin Rabbit pAb

Cat No.: APA3819
Size:
Product Name: Dystrophin Rabbit pAb
Cat No.: APA3819
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:2000
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Dystrophin
calculated molecular weight: 427 kDa
observed molecular weight: 427 kDa
genbank accession number: P11532
gene id (ncbi): 1756
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: BMD; CMD3B; MRX85; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272
category: Primary Ab
concentration: 0.5mg/ml
background: This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]
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