Nesprin3 Rabbit pAb
Cat No.: APA3806
Size：
| Product Name: | Nesprin3 Rabbit pAb |
| Cat No.: | APA3806 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000-1:2000 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human Nesprin3 |
| calculated molecular weight: | 112 kDa |
| observed molecular weight: | 112 kDa |
| genbank accession number: | Q6ZMZ3 |
| gene id (ncbi): | 161176 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | KASH3; NET53; Nesp3; C14orf49; C14orf139; LINC00341; NCRNA00341 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells. |