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APPBP1 Rabbit pAb

Cat No.: APA3804
Size:
Product Name: APPBP1 Rabbit pAb
Cat No.: APA3804
source: Rabbit
reactivity: Human, Rat
applications: WB,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:2000
FC: 1:20
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human APPBP1
calculated molecular weight: 60 kDa
observed molecular weight: 60 kDa
genbank accession number: Q13564
gene id (ncbi): 8883
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: HPP1; ula-1; APPBP1; A-116A10.1
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer--s disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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