VCAM1 Rabbit pAb
Cat No.: APA3769

Product Name: | VCAM1 Rabbit pAb |
Cat No.: | APA3769 |
source: | Rabbit |
reactivity: | Mouse |
applications: | WB,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of mouse VCAM1 |
calculated molecular weight: | 81 kDa |
observed molecular weight: | 100 kDa |
genbank accession number: | P29533 |
gene id (ncbi): | 22329 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | CD106; Vcam-1 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. |