FMO5 Rabbit pAb
Cat No.: APA3761
Size：
| Product Name: | FMO5 Rabbit pAb |
| Cat No.: | APA3761 |
| source: | Rabbit |
| reactivity: | Human, Mouse |
| applications: | WB,IHC,ICC/IF,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000-1:2000 IHC: 1:50-1:200 ICC/IF: 1:50 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human FMO5 |
| calculated molecular weight: | 60 kDa |
| observed molecular weight: | 60 kDa |
| genbank accession number: | P49326 |
| gene id (ncbi): | 2330 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | Dimethylaniline oxidase 5; Hepatic flavin-containing monooxygenase 5 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009] |