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MGA Rabbit pAb

Cat No.: APA3723
Size:
Product Name: MGA Rabbit pAb
Cat No.: APA3723
source: Rabbit
reactivity: Mouse
applications: WB
clonality: Polyclonal
recommended dilution: WB: 1:1000
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of mouse MGA
calculated molecular weight: 329 kDa
observed molecular weight: 400 kDa
genbank accession number: A2AWL7
gene id (ncbi): 29808
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: Mad5; C80739; AV312082; C130042M01Rik; D030062C11Rik
category: Primary Ab
concentration: 0.5mg/ml
background: Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5---AATTTCACACCTAGGTGTGAAATT-3-- core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor.
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