MGA Rabbit pAb
Cat No.: APA3723

Product Name: | MGA Rabbit pAb |
Cat No.: | APA3723 |
source: | Rabbit |
reactivity: | Mouse |
applications: | WB |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of mouse MGA |
calculated molecular weight: | 329 kDa |
observed molecular weight: | 400 kDa |
genbank accession number: | A2AWL7 |
gene id (ncbi): | 29808 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | Mad5; C80739; AV312082; C130042M01Rik; D030062C11Rik |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5---AATTTCACACCTAGGTGTGAAATT-3-- core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor. |