Integrin beta 4 Rabbit pAb
Cat No.: APA3700
Size：
| Product Name: | Integrin beta 4 Rabbit pAb |
| Cat No.: | APA3700 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,ICC/IF |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000-1:5000 ICC/IF: 1:50-1:200 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Integrin beta 4 |
| calculated molecular weight: | 202 kDa |
| observed molecular weight: | 202 kDa |
| genbank accession number: | P16144 |
| gene id (ncbi): | 3691 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | CD104; GP150 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |