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BRAT1 Rabbit pAb

Cat No.: APA2760
Size:
Product Name: BRAT1 Rabbit pAb
Cat No.: APA2760
source: Rabbit
reactivity: Human
applications: WB,ICC/IF,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:2000-1:10000
ICC/IF: 1:50
FC: 1:20
IP: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human BRAT1
calculated molecular weight: 88 kDa
observed molecular weight: 88 kDa
genbank accession number: Q6PJG6
gene id (ncbi): 221927
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: BAAT1; RMFSL; C7orf27
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM. [provided by RefSeq, Mar 2012]
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