DAZAP1 Rabbit pAb
Cat No.: APA2750
Size：
| Product Name: | DAZAP1 Rabbit pAb |
| Cat No.: | APA2750 |
| source: | Rabbit |
| reactivity: | Human, Rat |
| applications: | WB,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:2000-1:10000 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human DAZAP1 |
| calculated molecular weight: | 43 kDa |
| observed molecular weight: | 43 kDa |
| genbank accession number: | Q96EP5 |
| gene id (ncbi): | 26528 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | DAZ-associated protein 1; Deleted in azoospermia-associated protein 1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. This gene encodes a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008] |