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CYP27A1 Rabbit pAb

Cat No.: APA2632
Size:
Product Name: CYP27A1 Rabbit pAb
Cat No.: APA2632
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:50
ICC/IF: 1:20
FC: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human CYP27A1
calculated molecular weight: 60 kDa
observed molecular weight: 60 kDa
genbank accession number: Q02318
gene id (ncbi): 1593
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: CTX; CP27; CYP27
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. [provided by RefSeq, Jul 2008]
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