CYP27A1 Rabbit pAb
Cat No.: APA2632

Product Name: | CYP27A1 Rabbit pAb |
Cat No.: | APA2632 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,ICC/IF,FC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:50 ICC/IF: 1:20 FC: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human CYP27A1 |
calculated molecular weight: | 60 kDa |
observed molecular weight: | 60 kDa |
genbank accession number: | Q02318 |
gene id (ncbi): | 1593 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | CTX; CP27; CYP27 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. [provided by RefSeq, Jul 2008] |