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GDF7 Rabbit pAb

Cat No.: APA2602
Size:
Product Name: GDF7 Rabbit pAb
Cat No.: APA2602
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:50-1:500
ICC/IF: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human GDF7
calculated molecular weight: 47 kDa
observed molecular weight: 47 kDa
genbank accession number: Q7Z4P5
gene id (ncbi): 151449
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: BMP12
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett--s esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016]
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