HLA-DQA1 Rabbit pAb
Cat No.: APA2518
| Product Name: | HLA-DQA1 Rabbit pAb |
| Cat No.: | APA2518 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:2000-1:10000 IHC: 1:50 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human HLA-DQA1 |
| calculated molecular weight: | 28 kDa |
| observed molecular weight: | 28-35 kDa |
| genbank accession number: | P01909 |
| gene id (ncbi): | |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | DC-1 alpha chain; DC-alpha; HLA-DCA; MHC class II DQA1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. |
