LOX 1 Rabbit pAb
Cat No.: APA2516
| Product Name: | LOX 1 Rabbit pAb |
| Cat No.: | APA2516 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human LOX 1 |
| calculated molecular weight: | 31 kDa |
| observed molecular weight: | 50 kDa |
| genbank accession number: | P78380 |
| gene id (ncbi): | 4973 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | LOX1; LOXIN; SLOX1; CLEC8A; SCARE1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer--s disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010] |
