ALDH3A1 Rabbit pAb
Cat No.: APA2511
| Product Name: | ALDH3A1 Rabbit pAb |
| Cat No.: | APA2511 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,FC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 FC: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human ALDH3A1 |
| calculated molecular weight: | 50 kDa |
| observed molecular weight: | 50 kDa |
| genbank accession number: | P30838 |
| gene id (ncbi): | 218 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | ALDH3; ALDHIII |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008] |
