BNP Rabbit pAb
Cat No.: APA2249

Product Name: | BNP Rabbit pAb |
Cat No.: | APA2249 |
source: | Rabbit |
reactivity: | Human |
applications: | WB |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000-1:5000 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human BNP |
calculated molecular weight: | 15 kDa |
observed molecular weight: | 30 kDa |
genbank accession number: | P16860 |
gene id (ncbi): | 4879 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | BNP |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein--s biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq, Nov 2014] |