gamma Sarcoglycan Rabbit pAb
Cat No.: APA1908

Product Name: | gamma Sarcoglycan Rabbit pAb |
Cat No.: | APA1908 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IHC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:100 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of human gamma Sarcoglycan |
calculated molecular weight: | 32 kDa |
observed molecular weight: | 32 kDa |
genbank accession number: | Q13326 |
gene id (ncbi): | 6445 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | A4; MAM; DMDA; SCG3; 35DAG; DAGA4; DMDA1; LGMD2C; LGMDR5; SCARMD2; gamma-SG |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008] |