PADI3/PAD3 Rabbit pAb
Cat No.: APA1854

Product Name: | PADI3/PAD3 Rabbit pAb |
Cat No.: | APA1854 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human PADI3/PAD3 |
calculated molecular weight: | 75 kDa |
observed molecular weight: | 75 kDa |
genbank accession number: | Q9ULW8 |
gene id (ncbi): | 51702 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | PAD3; PDI3; UHS1 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008] |