DMGDH Rabbit pAb
Cat No.: APA1844

Product Name: | DMGDH Rabbit pAb |
Cat No.: | APA1844 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IHC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:20 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human DMGDH |
calculated molecular weight: | 97 kDa |
observed molecular weight: | 97 kDa |
genbank accession number: | Q9UI17 |
gene id (ncbi): | 29958 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | DMGDHD; ME2GLYDH |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |