IL-13 Rabbit pAb
Cat No.: APA1813

Product Name: | IL-13 Rabbit pAb |
Cat No.: | APA1813 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human IL-13 |
calculated molecular weight: | 16 kDa |
observed molecular weight: | 12 kDa |
genbank accession number: | P35225 |
gene id (ncbi): | 3596 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | P600; IL-13 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008] |