Fluor® Violet 450 Anti-Human CD62L Antibody[HI62L]
Cat No.: FCE3785
Size:
Product Name: | Fluor® Violet 450 Anti-Human CD62L Antibody[HI62L] |
Cat No.: | FCE3785 |
host: | Mouse |
uniprot id: | P14151 |
geneid: | |
application: | FCM |
isotype: | Mouse IgG2a, κ |
form: | Liquid |
storage: | This product can be stored at 2-8°C for 12 months. Do not freeze. |
shipping: | Ice bag |
category id: | Flow Cytometry Antibodies |
abbreviation: | CD62L |
conjugation: | Fluor® Violet 450 |
species reactivity: | Human |
usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
clone no.: | HI62L |
background: | CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of na?ve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer--s patches. It also plays a role in leukocyte rolling on activated endothelial cells. |
target synonym: | L-selectin;Sell;CD62antigen-likefamilymemberL;LAM-1;LECAM1;Lymphnodehomingreceptor;Ly-22;CD62L;Lnhr;Ly22; |
concentration: | 5 μL/Test |
buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
image 1 description: | Human peripheral blood lymphocytes are stained with APC Anti-Human CD4 Antibody and Fluor® Violet 450 Anti-Human CD62L Antibody[HI62L] (Left). Lymphocytes are stained with APC Anti-Human CD4 Antibody and Fluor® Violet 450 Mouse IgG2a, κ Isotype Control (Right). |