FITC Anti-Human CD193/CCR3 Antibody[5E8]
Cat No.: FCE3735
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| Product Name: | FITC Anti-Human CD193/CCR3 Antibody[5E8] |
| Cat No.: | FCE3735 |
| host: | Mouse |
| uniprot id: | P51677 |
| geneid: | 1232 |
| application: | FCM |
| isotype: | Mouse IgG2b, κ |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | CD193/CCR3 |
| conjugation: | FITC |
| species reactivity: | Human |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| clone no.: | 5E8 |
| background: | CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+?hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types. |
| target synonym: | CC CKR3; MIP1-alpha receptor like-2; eotaxin receptor;CCR;C-C chemokine receptor type 3; |
| concentration: | 5 μL/Test |
| buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| image 1 description: | Human peripheral blood granulocytes are stained with APC Anti-Human CD16 Antibody and FITC Anti-Human CD193/CCR3 Antibody (Left). Granulocytes are stained with APC Anti-Human CD16 Antibody and FITC Mouse IgG2b,κ Isotype Control (Right). |
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