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Fluor® 647 Anti-Mouse CD163 Antibody[S15049F]

Cat No.: FCE3727
Size:
Product Name: Fluor® 647 Anti-Mouse CD163 Antibody[S15049F]
Cat No.: FCE3727
host: Rat
uniprot id: Q2VLH6
geneid: 93671
application: FCM
isotype: Rat IgG2a, κ
form: Liquid
storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
shipping: Ice bag
category id: Flow Cytometry Antibodies
abbreviation: CD163
conjugation: Fluor® 647
species reactivity: Mouse
usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
clone no.: S15049F
background: CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.
target synonym: M130; MM130; SCARI1;
concentration: 5 μL/Test
buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
image 1 description: C57BL/6 murine bone marrow cells are stained with FITC Anti-Mouse/Human CD11b Antibody and Fluor® 647 Anti-Mouse CD163 Antibody (Left). Bone marrow cells are stained with FITC Anti-Mouse/Human CD11b Antibody and Fluor® 647 Rat IgG2a,κ Isotype Control (Right).
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