Fluor® Violet 450 Anti-Human/Mouse KLRG-1 Antibody[2F1]
Cat No.: FCE3694
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| Product Name: | Fluor® Violet 450 Anti-Human/Mouse KLRG-1 Antibody[2F1] |
| Cat No.: | FCE3694 |
| host: | Syrian Hamster |
| uniprot id: | Q96E93;O88713; |
| geneid: | 10219,50928 |
| application: | FCM |
| isotype: | Syrian Hamster IgG |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | KLRG-1 |
| conjugation: | Fluor® Violet 450 |
| species reactivity: | Human,Mouse |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume]. |
| clone no.: | 2F1 |
| background: | Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag).? KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3.? It is composed of a homodimer of glycosylated 30-38 kD subunits.? Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells.? KLRG1 is also expressed on subsets of CD8+?and CD4+?cells, including CD4+?and CD8+?effector/memory cells, potent regulatory CD4+?T cells.? KLRG1 may be involved in regulating NK cell homeostasis.? KLRG33 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells. |
| target synonym: | MAFA; 2F1-Ag; |
| concentration: | 0.5 mg/mL |
| buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
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