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PE Anti-Human/Mouse KLRG-1 Antibody[2F1]

Cat No.: FCE3691
Size:
Product Name: PE Anti-Human/Mouse KLRG-1 Antibody[2F1]
Cat No.: FCE3691
host: Syrian Hamster
uniprot id: Q96E93;O88713;
geneid: 10219,50928
application: FCM
isotype: Syrian Hamster IgG
form: Liquid
storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
shipping: Ice bag
category id: Flow Cytometry Antibodies
abbreviation: KLRG-1
conjugation: PE
species reactivity: Human,Mouse
usage: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].
clone no.: 2F1
background: Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag).? KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3.? It is composed of a homodimer of glycosylated 30-38 kD subunits.? Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells.? KLRG1 is also expressed on subsets of CD8+?and CD4+?cells, including CD4+?and CD8+?effector/memory cells, potent regulatory CD4+?T cells.? KLRG1 may be involved in regulating NK cell homeostasis.? KLRG21 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.
target synonym: MAFA; 2F1-Ag;
concentration: 0.2 mg/mL
buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
image 1 description: C57BL/6 murine splenocytes are stained with APC Anti-Mouse CD161/NK1.1 Antibody and PE Anti-Human/Mouse KLRG-1 Antibody (Left). Splenocytes are stained with APC Anti-Mouse CD161/NK1.1 Antibody and PE Syrian Hamster IgG Isotype Control (Right).
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