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FITC Anti-Mouse CD200/OX2 Antibody[OX-90]

Cat No.: FCE3605
Size:
Product Name: FITC Anti-Mouse CD200/OX2 Antibody[OX-90]
Cat No.: FCE3605
host: Rat
uniprot id: O54901
geneid: 4345
application: FCM
isotype: Rat IgG2a, κ
form: Liquid
storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
shipping: Ice bag
category id: Flow Cytometry Antibodies
abbreviation: CD200/OX2
conjugation: FITC
species reactivity: Mouse
usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
clone no.: OX-90
background: CD200 (OX-2 antigen) is a type-1 membrane glycoprotein containing two extracellular Ig-like domains. CD200 a highly conserved type I membrane glycoprotein that is expressed on a variety of cell types including thymocytes, some T cells, endothelial and follicular dendritc cells,?B cells,?and brain tissue (neurons); but not on NK cells, granulocytes, monocytes, or macrophages.? CD200 costimulates T cell proliferation. It may regulate myeloid cell activity in a variety of tissues.? CD200 is the ligand for CD200 receptor (CD200R).? The CD200 Receptor is restricted to myeloid cells, and it is believed that its engagement with CD200 results in inhibition and/or downregulation of myeloid cell activity.? Blocking of CD200/CD200R interactions decreases myeloid cell inhibitory thresholds which results in enhanced immune activation.
target synonym: OX-2 membrane glycoprotein;OX-2; MRC;
concentration: 5 μL/Test
buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
image 1 description: C57BL/6 murine splenocytes are stained with APC Anti-Mouse CD45R/B220 Antibody and FITC Anti-Mouse CD200 Antibody (Left). Splenocytes are stained with APC Anti-Mouse CD45R/B220 Antibody and FITC Rat IgG2a, κ Isotype Control (Right).