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PE/Cyanine7 Anti-Human CD80 Antibody[2D10]

Cat No.: FCE3599
Size:
Product Name: PE/Cyanine7 Anti-Human CD80 Antibody[2D10]
Cat No.: FCE3599
host: Mouse
uniprot id: P33681
geneid: 941
application: FCM
isotype: Mouse IgG1, κ
form: Liquid
storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
shipping: Ice bag
category id: Flow Cytometry Antibodies
abbreviation: CD80
conjugation: PE/Cyanine7
species reactivity: Human
usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
clone no.: 2D10
background: CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
target synonym: T-lymphocyte activation antigen CD80;B7-1; B7; BB1;
concentration: 5 μL/Test
buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
image 1 description: Daudi (human B Burkitt--s lymphoma cell line) cells are stained with PE/Cyanine7 Anti-Human CD80 Antibody (filled gray histogram).Unstained Daudi cells (empty black histogram) are used as control.