Fluor® 647 Anti-Human CD11a Antibody[R7-1]
Cat No.: FCE3464
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| Product Name: | Fluor® 647 Anti-Human CD11a Antibody[R7-1] |
| Cat No.: | FCE3464 |
| host: | Mouse |
| uniprot id: | P20701 |
| geneid: | 3683 |
| application: | FCM |
| isotype: | Mouse IgG1, κ |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | CD11a |
| conjugation: | Fluor® 647 |
| species reactivity: | Human |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| clone no.: | R7-1 |
| background: | CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50). |
| target synonym: | Integrin alpha-L;LFA-1A;CD11A;ITGAL; |
| concentration: | 5 μL/Test |
| buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| image 1 description: | Human peripheral blood lymphocytes are stained with Fluor® 647 Anti-Human CD11a Antibody (filled gray histogram) or Fluor® 647 Mouse IgG1, κ Isotype Control (empty black histogram). |
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