Purified Anti-Human IL-4 Antibody[MP4-25D2]
Cat No.: FCE3420
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| Product Name: | Purified Anti-Human IL-4 Antibody[MP4-25D2] |
| Cat No.: | FCE3420 |
| host: | Rat |
| uniprot id: | P05112 |
| geneid: | 3565 |
| application: | ICFCM,ELISA |
| isotype: | Rat IgG1, κ |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | IL-4 |
| conjugation: | Unconjugated |
| species reactivity: | Human |
| usage: | Each lot of this antibody is quality control tested by ELISA assay. Purified MP4-25D2 has been tested by blocking fluorochrome conjugated MP4-25D2 for intracellular cytokine staining. In order to obtain complete blocking results, a saturated amount of purified antibody (≤ 5.0 µg/million cells) should be used for incubation with target cells, prior to staining with fluorochrome conjugated antibody. It is recommended that the reagent be titrated for optimal performance for each application. |
| clone no.: | MP4-25D2 |
| background: | IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells, and basophils. IL-4 elicits many different biological responses but has two dominant functions. The first is regulating differentiation of na?ve CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10, and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells. |
| target synonym: | Interleukin-4;IL-4;B-cell IgG differentiation factor;B-cell growth factor 1;BSF-1;IGG1 induction factor; |
| concentration: | 0.5 mg/mL |
| buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
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