APC Anti-Mouse IL-10 Antibody[JES5-16E3]
Cat No.: FCE3391
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| Product Name: | APC Anti-Mouse IL-10 Antibody[JES5-16E3] |
| Cat No.: | FCE3391 |
| host: | Rat |
| uniprot id: | P18893 |
| geneid: | 16153 |
| application: | ICFCM |
| isotype: | Rat IgG2b, κ |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | IL-10 |
| conjugation: | APC |
| species reactivity: | Mouse |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume]. |
| clone no.: | JES5-16E3 |
| background: | L-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, TNF-β, and IL-2 production by Th1 clones; inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis; suppresses the delayed type hypersensitivity response; stimulates Th2 cell response (which results in elevated antibody production); and promotes mast cell proliferation in combination with IL-4. |
| target synonym: | Interleukin-10;IL-10;Cytokine synthesis inhibitory factor;CSIF; |
| concentration: | 0.2 mg/mL |
| buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| image 1 description: | HEK293T cells transiently transfected with pcDNA3.1 plasmid encoding Mouse IL-10 gene are stained with APC Anti-Mouse IL-10 Antibody (filled gray histogram) or APC Rat IgG2b, κ lsotype Control (empty black histogram). |
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