PerCP/Cyanine5.5 Anti-Human CD28 Antibody[CD28.2]
Cat No.: FCE3377
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| Product Name: | PerCP/Cyanine5.5 Anti-Human CD28 Antibody[CD28.2] |
| Cat No.: | FCE3377 |
| host: | Mouse |
| uniprot id: | P10747 |
| geneid: | 940 |
| application: | FCM |
| isotype: | Mouse IgG1, κ |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | CD28 |
| conjugation: | PerCP/Cyanine5.5 |
| species reactivity: | Human |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| clone no.: | CD28.2 |
| background: | CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation. |
| target synonym: | PAS2;MNS;HGpMiX;GYPA;GPSAT; |
| concentration: | 5 μL/Test |
| buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| image 1 description: | Human peripheral blood lymphocytes are stained with PerCP/Cyanine5.5 Anti-Human CD28 Antibody (filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control. |
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