PE Anti-Mouse CD366/Tim-3 Antibody[RMT3-23]
Cat No.: FCE3348
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| Product Name: | PE Anti-Mouse CD366/Tim-3 Antibody[RMT3-23] |
| Cat No.: | FCE3348 |
| host: | Rat |
| uniprot id: | Q8VIM0 |
| geneid: | 84868 |
| application: | FCM |
| isotype: | Rat IgG2a, κ |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | CD366/Tim-3 |
| conjugation: | PE |
| species reactivity: | Mouse |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume]. |
| clone no.: | RMT3-23 |
| background: | CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance. |
| target synonym: | TIM3; TIMD3;HAVcr-2;TIMD-3; |
| concentration: | 0.2 mg/mL |
| buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| image 1 description: | C57BL/6 murine splenocytes are stained with APC Anti-Mouse CD4 Antibody and PE Anti-Mouse CD366/Tim-3 Antibody (Left). Splenocytes are stained with APC Anti-Mouse CD4 Antibody and PE Rat IgG2a, κ Isotype Control (Right). |