AF/LE Purified Anti-Mouse CD366/Tim-3 Antibody[RMT3-23]
Cat No.: FCE3342
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| Product Name: | AF/LE Purified Anti-Mouse CD366/Tim-3 Antibody[RMT3-23] |
| Cat No.: | FCE3342 |
| host: | Rat |
| uniprot id: | Q8VIM0 |
| geneid: | 84868 |
| application: | FCM,Block |
| isotype: | Rat IgG2a, κ |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | CD366/Tim-3 |
| conjugation: | None (Purified antibody-Azide Free/Low endotoxin) |
| species reactivity: | Mouse |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| clone no.: | RMT3-23 |
| background: | CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance. |
| target synonym: | TIM3; TIMD3;HAVcr-2;TIMD-3; |
| concentration: | 0.5 mg/mL |
| buffer: | 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
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