PE/Cyanine5.5 Anti-Mouse Ly6A/E(Sca-1) Antibody[D7]
Cat No.: FCE3337
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| Product Name: | PE/Cyanine5.5 Anti-Mouse Ly6A/E(Sca-1) Antibody[D7] |
| Cat No.: | FCE3337 |
| host: | Rat |
| uniprot id: | P05533 |
| geneid: | 110454 |
| application: | FCM |
| isotype: | Rat IgG2a, κ |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | Ly6A/E(Sca-1) |
| conjugation: | PE/Cyanine5.5 |
| species reactivity: | Mouse |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume]. |
| clone no.: | D7 |
| background: | Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses. |
| target synonym: | Ly6a;Ly6;Ly-6A.2/Ly-6E.1;SCA-1;TAP; |
| concentration: | 0.2 mg/mL |
| buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| image 1 description: | C57BL/6 murine splenocytes are stained with PE/Cyanine5.5 Anti-Mouse Ly6A/E(Sca-1) Antibody (filled gray histogram) or PE/Cyanine5.5 Rat IgG2a, κ Isotype Control (empty black histogram). |
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