APC Anti-Mouse FcεRIα Antibody[MAR-1]
Cat No.: FCE3278
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| Product Name: | APC Anti-Mouse FcεRIα Antibody[MAR-1] |
| Cat No.: | FCE3278 |
| host: | Armenian Hamster |
| uniprot id: | P20489 |
| geneid: | 14125 |
| application: | FCM |
| isotype: | Armenian Hamster IgG |
| form: | Liquid |
| storage: | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| shipping: | Ice bag |
| category id: | Flow Cytometry Antibodies |
| abbreviation: | FcεRIα |
| conjugation: | APC |
| species reactivity: | Mouse |
| usage: | Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume]. |
| clone no.: | MAR-1 |
| background: | FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit. |
| target synonym: | High affinity immunoglobulin epsilon receptor subunit alpha;Fc-epsilon RI-alpha;FcERI;Fcer1a; |
| concentration: | 0.2 mg/mL |
| buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| image 1 description: | C57BL/6 murine bone marrow cells are stained with PE Anti-Mouse CD49b Antibody and APC Anti-Mouse FcεRIα Antibody (Left). Bone marrow cells are stained with PE Anti-Mouse CD49b Antibody and APC Armenian Hamster IgG Isotype Control (Right). |